ConditionChildren's health

Herpangina

Herpangina is a common viral infection, mostly in children aged 3 to 10, that causes a sudden fever and small, painful blisters and ulcers at the back of the mouth and throat. It is caused by enteroviruses, especially coxsackie A viruses, the same family behind hand, foot and mouth disease. It peaks in summer and fall, is contagious, and usually clears within 7 to 10 days. The main risk is dehydration when swallowing hurts, so keeping a child drinking is the priority.

Also called: Vesicular pharyngitis, coxsackievirus pharyngitis, enteroviral pharyngitis

At a glance

Cause
Enteroviruses, mostly coxsackievirus A.
Who gets it
Mostly children aged 3 to 10. Adults occasionally.
Symptoms
Sudden fever, sore throat, painful small sores on the back of the roof of the mouth and tonsils.
Duration
Fever 2 to 4 days. Sores heal within 7 to 10 days.
Treatment
Fluids, pain and fever relief. Antibiotics do not help.

When to get help

Call 911 or go to the ER

  • Signs of severe dehydration: no urine for 8 hours or more, very dry mouth, no tears, sunken eyes, or a very sleepy, floppy child
  • Stiff neck, severe headache, confusion, a seizure or unusual weakness (rare enterovirus complications)
  • Difficulty breathing, or chest pain with a racing heart

See a doctor within a day or two

  • A baby under 3 months with a fever of 38 °C (100.4 °F) or higher
  • Refusing all drinks for more than a few hours
  • Fever above 40 °C (104 °F), or fever lasting more than 3 days
  • Sores that are still present after 10 days, or large sores on the gums and lips

Book a routine appointment

  • Symptoms in a child with a weakened immune system

Usually safe to manage at home

  • Fever and a sore mouth with small ulcers at the back of the throat in a child who is still drinking

Symptoms

Symptoms begin 3 to 6 days after exposure and come on suddenly:

  • fever, often 38.9 to 40 °C (102 to 104 °F)
  • sore throat and painful swallowing
  • small grayish blisters, 1 to 2 mm, on the soft palate (back of the roof of the mouth), uvula, tonsils and back of the throat, which break into shallow, red-rimmed ulcers
  • typically 2 to 12 sores
  • drooling, refusing food and drinks in young children
  • headache, neck pain, tiredness and loss of appetite
  • sometimes vomiting or belly pain

The fever usually lasts 2 to 4 days, and the sores heal within 7 to 10 days.

Herpangina vs similar conditions

ConditionWhere sores appearOther clues
HerpanginaBack of the mouth: soft palate, tonsils, uvulaNo rash on hands or feet
Hand, foot and mouth diseaseFront of mouth, tongue and cheeks, plus backSpots or blisters on hands, feet, buttocks
Herpes gingivostomatitisFront of mouth, gums and lipsSwollen, bleeding gums
Strep throatNo ulcers. Red tonsils, sometimes white patchesSwollen neck glands, no cough. Needs antibiotics
Canker soresInside lips and cheeksNo fever. Recur

How herpangina spreads

Enteroviruses spread through:

  • saliva, nasal mucus and droplets from coughs and sneezes
  • stool, especially during diaper changes and toilet use
  • contaminated hands, toys and surfaces

Children are most contagious during the first week, but the virus can remain in stool for several weeks after symptoms clear. Outbreaks are common in childcare and schools in summer and early fall.

Diagnosis

Herpangina is diagnosed by looking at the mouth and throat. The typical location of the sores at the back of the mouth, with fever and no hand or foot rash, is usually enough. Tests are rarely needed but may be used to rule out strep throat or in severe cases.

Treatment and home care

There is no specific antiviral treatment, and antibiotics do not work against viruses. The goal is comfort and hydration.

Keep your child drinking

  • offer small, frequent sips of cool water, milk or oral rehydration solution
  • cold foods and drinks, such as ice pops, smoothies, yogurt and ice cream, soothe the throat
  • avoid acidic, salty or spicy foods and juices like orange juice, which sting
  • a straw or spoon may help if drinking from a cup hurts
  • soft foods such as mashed potatoes, pasta and soup (lukewarm)

Pain and fever relief

  • acetaminophen (paracetamol) or ibuprofen at the dose for your child's weight. Ibuprofen is not for babies under 6 months. Do not give aspirin to children or teenagers.
  • giving pain relief 30 minutes before meals can make eating and drinking easier
  • for children old enough not to swallow it, rinsing with salt water can soothe
  • avoid numbing gels containing benzocaine in children under 2

Preventing spread

  • wash hands often with soap and water, especially after diaper changes and toilet use
  • avoid sharing cups, utensils and towels
  • clean toys and frequently touched surfaces
  • keep children home from childcare or school while they have a fever and are unwell, and until they feel well enough to participate

Herpangina in adults

Adults can get herpangina, usually from a child in the household. Symptoms are similar but often milder. Many adults have immunity from childhood infections.

Complications

Most children recover completely. Possible complications include:

  • dehydration, the most common reason for a hospital visit
  • rarely, enteroviruses cause viral meningitis, encephalitis or inflammation of the heart muscle (myocarditis)
  • newborns can develop more severe disease

Frequently asked questions

What does herpangina look like?

Herpangina causes small grayish blisters at the back of the roof of the mouth, the uvula and around the tonsils. They burst into shallow ulcers with red borders. There is usually no rash on the hands or feet, which distinguishes it from hand, foot and mouth disease.

How long is herpangina contagious?

Children are most contagious in the first week of illness. However, the virus can be shed in stool for several weeks after symptoms go away, so good handwashing is important even after recovery.

How long does herpangina last?

The fever usually lasts 2 to 4 days, and the mouth sores heal within 7 to 10 days. Most children feel much better within a few days, though eating may be uncomfortable for about a week.

Can adults get herpangina?

Yes, though it is much less common than in children. Adults usually catch it from a child and often have milder symptoms. Treatment is the same: fluids, pain relief and rest.

Sources

This guide was written from current patient and clinical guidance, including:

  • American Academy of Pediatrics (HealthyChildren.org): Hand, foot and mouth disease and herpangina
  • CDC: Non-polio enterovirus
  • MedlinePlus: Herpangina
  • Merck Manual Professional Version: Herpangina
  • NHS: Hand, foot and mouth disease