Medical glossary
Short, plain-English definitions of the medical words you are most likely to meet in a doctor's letter, a test result or a health article. Where we have a full guide on the topic, the term links to it.
Jump to a letter: A · B · C · D · E · F · G · H · I · J · L · M · N · O · P · R · S · T · U · V · W · X
A
Abscess
A pocket of pus walled off inside the body, caused by a bacterial infection. Many need to be drained. See abscess.
Acute
Starting suddenly or lasting a short time, such as acute bronchitis. It describes timing, not severity.
Anaphylaxis
A severe, whole-body allergic reaction that can block the airway and drop blood pressure within minutes. It is treated with epinephrine and is always an emergency. See anaphylaxis.
Anemia
Having too few healthy red blood cells or too little hemoglobin, so less oxygen reaches the tissues. It often causes tiredness and pale skin. See anemia.
Aneurysm
A weak spot in a blood vessel wall that bulges outward like a balloon. A burst aneurysm causes severe internal bleeding. See aortic aneurysm.
Angina
Chest pain or pressure caused by too little blood flow to the heart muscle, usually brought on by exertion and eased by rest. See angina.
Antibiotic
A medicine that kills bacteria or stops them from growing. Antibiotics do not work against viruses such as colds and flu.
Antibody
A protein made by the immune system that recognizes and helps destroy a specific germ or foreign substance. Blood tests for antibodies can show past infection or vaccination.
Anticoagulant
A medicine that slows blood clotting, often called a blood thinner. It is used to prevent and treat clots and raises the risk of bleeding.
Antihistamine
A medicine that blocks histamine, a chemical released in allergic reactions. It eases itching, sneezing and hives, and older types cause drowsiness.
Aphasia
Difficulty speaking, understanding, reading or writing language, usually after damage to the brain such as a stroke. See aphasia.
Arrhythmia
An abnormal heart rhythm: too fast, too slow or irregular. See arrhythmia.
Arthralgia
Pain in a joint, without necessarily any swelling. See joint pain.
Ataxia
Poor coordination of movement, causing an unsteady walk, clumsy hands or slurred speech. See ataxia.
B
Benign
Not cancerous and not spreading to other parts of the body. A benign growth can still cause problems if it presses on nearby structures.
Biopsy
Removing a small sample of tissue so it can be examined under a microscope. It is the main way to confirm or rule out cancer.
Bradycardia
A slow heart rate, usually under 60 beats a minute at rest in adults. It is normal in many fit people. See bradycardia.
Bronchitis
Inflammation of the main airways in the lungs, causing a cough that often brings up mucus. See acute bronchitis.
C
Cardiac arrest
When the heart suddenly stops pumping effectively, so the person collapses and stops breathing normally. It needs CPR and a defibrillator within minutes. See cardiac arrest.
Cellulitis
A bacterial infection of the deeper layers of the skin, causing a spreading area of red, warm, swollen and tender skin. See cellulitis.
Chronic
Lasting a long time, usually more than 3 months, or coming back again and again. Like "acute", it describes timing, not severity.
Comorbidity
Another illness a person has at the same time as the main condition, such as diabetes in someone with heart disease.
Contraindication
A reason not to use a particular treatment, because it could be harmful. For example, a stomach ulcer is a contraindication to ibuprofen.
CT scan
Computed tomography: a scan that uses X-rays and a computer to make detailed cross-section pictures of the body. It is fast and widely used in emergencies.
Cyanosis
A blue or gray tinge to the lips, skin or nail beds, caused by low oxygen in the blood. New cyanosis is an emergency.
D
Dehydration
Losing more fluid than you take in, so the body lacks the water it needs. Signs include thirst, dark urine and dizziness. See dehydration.
Dermatitis
Inflammation of the skin, causing redness, itching and sometimes blistering or flaking. Eczema is a common type. See dermatitis.
Diagnosis
The identification of the disease or condition causing a person's symptoms.
Differential diagnosis
The list of possible conditions that could explain a set of symptoms, which a doctor narrows down with questions, an exam and tests.
Dysphagia
Difficulty swallowing, or a feeling that food sticks on the way down. See difficulty swallowing.
Dyspnea
Shortness of breath, or the feeling of not getting enough air. See dyspnea.
Dysuria
Pain, burning or discomfort when passing urine, often from a urinary tract infection. See painful urination.
E
ECG
Electrocardiogram (also EKG): a quick, painless test that records the heart's electrical activity using stickers on the chest. It helps detect heart attacks and rhythm problems.
Edema
Swelling caused by fluid trapped in the body's tissues, most often in the feet, ankles and legs. See edema.
Embolism
A blockage in a blood vessel caused by material carried in the bloodstream, usually a blood clot. See pulmonary embolism.
Endoscopy
Looking inside the body with a thin, flexible tube that has a light and camera on the end. Colonoscopy is a type of endoscopy.
Epinephrine
Also called adrenaline: a hormone and medicine that opens the airways and raises blood pressure. An epinephrine auto-injector is the first treatment for anaphylaxis.
Etiology
The cause or origin of a disease.
F
Febrile
Having a fever. A febrile seizure is a seizure in a young child caused by a fever.
Fever
A body temperature of 38 °C (100.4 °F) or higher, usually a sign the body is fighting an infection. See fever.
Fracture
A broken bone, from a hairline crack to a complete break. See bone fracture.
G
Gastritis
Inflammation of the stomach lining, causing upper belly pain, nausea or indigestion. See gastritis.
Generic drug
A medicine with the same active ingredient, strength and effect as a brand-name drug, usually sold at a lower price.
GERD
Gastroesophageal reflux disease: frequent backflow of stomach acid into the esophagus (food pipe), causing heartburn. See GERD.
H
Hematemesis
Vomiting blood, which may look bright red or like coffee grounds. It needs emergency care. See vomiting blood.
Hematuria
Blood in the urine, either visible or found only on a test. See hematuria.
Hemoglobin
The iron-containing protein in red blood cells that carries oxygen. A low level means anemia.
Hemoptysis
Coughing up blood or blood-streaked mucus from the lungs. See hemoptysis.
Hernia
When an organ or fatty tissue pushes through a weak spot in the muscle wall that holds it in, often making a bulge in the groin or belly. See hernia.
Hives
Raised, itchy welts on the skin that come and go, often from an allergy. The medical name is urticaria. See hives.
Hypertension
High blood pressure: pressure in the arteries that stays at or above 130/80 mm Hg by current US guidelines. It usually causes no symptoms. See high blood pressure.
Hypoglycemia
Low blood sugar, usually below 70 mg/dL (3.9 mmol/L). It causes shakiness, sweating and confusion, and is most common in people treated for diabetes. See hypoglycemia.
Hypotension
Low blood pressure. It is often harmless but can cause dizziness or fainting. See hypotension.
Hypoxia
Too little oxygen reaching the body's tissues. It can cause breathlessness, confusion and a blue tinge to the skin.
I
Idiopathic
Having no known cause.
Immunocompromised
Having a weakened immune system, from a disease or from medicines such as chemotherapy or steroids, so infections are more likely and can be more serious.
Infection
Invasion of the body by germs such as bacteria, viruses, fungi or parasites that multiply and cause illness. See infection.
Inflammation
The body's response to injury or infection, causing redness, heat, swelling and pain. Long-lasting inflammation can damage tissue.
Insomnia
Trouble falling asleep, staying asleep, or waking too early, at least 3 nights a week. See insomnia.
Ischemia
Reduced blood flow to a part of the body, starving it of oxygen. Ischemia of the heart causes angina; prolonged ischemia causes tissue death.
J
Jaundice
Yellowing of the skin and the whites of the eyes, caused by a buildup of bilirubin, a pigment the liver normally clears. See jaundice.
L
Lesion
Any abnormal area of tissue, such as a sore, lump, patch or spot. The word does not say whether it is harmless or serious.
Lethargy
Abnormal drowsiness, sluggishness or lack of energy. See lethargy.
Lymph nodes
Small, bean-shaped glands in the neck, armpits, groin and elsewhere that filter fluid and help fight infection. They swell during infections. See swollen lymph nodes.
M
Malaise
A general feeling of being unwell, uncomfortable or "off", without one specific symptom.
Malignant
Cancerous: able to invade nearby tissue and spread to other parts of the body. See cancer.
Melena
Black, sticky, tar-like stools caused by bleeding high in the digestive tract. See melena.
Metastasis
Spread of cancer from where it started to another part of the body. See metastatic cancer.
MRI
Magnetic resonance imaging: a scan that uses a strong magnet and radio waves, not X-rays, to make detailed pictures, especially of the brain, spine and joints.
Myalgia
Muscle pain or aching. See muscle pain.
N
Nausea
An uneasy feeling in the stomach with an urge to vomit. See nausea.
Necrosis
Death of body tissue, usually from loss of blood supply, infection or injury.
Neuralgia
Sharp, shooting or burning pain along the path of a nerve. See neuralgia.
Neuropathy
Damage to nerves, often causing numbness, tingling or burning in the feet and hands. Diabetes is a common cause. See peripheral neuropathy.
Nocturia
Waking up at night one or more times to pass urine. See nocturia.
NSAID
Nonsteroidal anti-inflammatory drug: a group of pain relievers that also reduce inflammation, including ibuprofen, naproxen and aspirin. See medication safety.
O
Orthopnea
Shortness of breath when lying flat that eases on sitting up. It can be a sign of heart failure.
OTC
Over the counter: medicines you can buy without a prescription.
Otitis media
Infection or inflammation of the middle ear, behind the eardrum, common in young children. See otitis media.
P
Palliative care
Care focused on relieving symptoms and improving quality of life in serious illness. It can be given alongside treatment aimed at a cure.
Palpitations
Being aware of your own heartbeat: pounding, fluttering, racing or skipped beats. See heart palpitations.
Paresthesia
Tingling, prickling or "pins and needles" in the skin. See paresthesia.
Pathogen
Any germ that can cause disease, such as a bacterium, virus, fungus or parasite.
Prognosis
The likely course and outcome of a disease, including the chance of recovery.
Prophylaxis
Treatment given to prevent a disease rather than to treat it, such as a vaccine or antibiotics before some surgery.
Pruritus
Itching. See pruritus.
Pulse oximeter
A small clip on the finger that estimates the oxygen level in the blood. Normal readings are usually 95% to 100%. Readings can be less accurate on darker skin.
R
Referred pain
Pain felt in a different place from its source. For example, a heart attack can cause pain in the jaw or arm.
Remission
A period when the signs and symptoms of a disease lessen or disappear. It may be partial or complete.
Rhinorrhea
A runny nose. See runny nose.
S
Sepsis
A life-threatening reaction to an infection in which the body's response damages its own organs. See sepsis.
Sign
Something a doctor can observe or measure, such as a rash, a fever or a heart murmur. A symptom is something you feel and report, such as pain or nausea.
Stenosis
Abnormal narrowing of a passage in the body, such as a blood vessel, heart valve or the spinal canal. See aortic stenosis.
Stroke
Sudden loss of brain function caused by a blocked or burst blood vessel in the brain. It is a medical emergency. See stroke.
Syncope
Fainting: a brief loss of consciousness caused by a temporary drop in blood flow to the brain. See syncope.
Systemic
Affecting the whole body rather than one part.
T
Tachycardia
A fast heart rate, over 100 beats a minute at rest in adults. See tachycardia.
Thrombosis
A blood clot forming inside a blood vessel and blocking blood flow. See deep vein thrombosis.
TIA
Transient ischemic attack, or "mini-stroke": stroke symptoms that go away within minutes to hours. It is a warning sign and needs emergency assessment. See TIA.
Tinnitus
Hearing ringing, buzzing or hissing sounds that have no outside source. See tinnitus.
Triage
Sorting patients by how urgently they need care, so the sickest are seen first.
U
Ultrasound
A scan that uses sound waves to make pictures of organs, blood vessels or a baby in the womb. It uses no radiation.
Urticaria
The medical name for hives. See urticaria.
V
Vaccine
A preparation that trains the immune system to recognize a germ, so the body can fight it off faster in the future.
Vertigo
A false feeling that you or your surroundings are spinning or moving. It usually comes from the inner ear. See vertigo.
Virus
A tiny germ that can only multiply inside living cells. Viruses cause colds, flu and COVID-19, and antibiotics do not kill them.
Vital signs
Basic measurements of body function: temperature, pulse, breathing rate, blood pressure and often oxygen level.
W
Wheezing
A high-pitched whistling sound on breathing, caused by narrowed airways, as in asthma. See wheezing.
X
X-ray
A quick imaging test that uses a small dose of radiation to show bones and some organs, such as the lungs.
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