ConditionBones, joints & muscles
Degenerative Disc Disease
Degenerative disc disease (DDD) describes age-related changes in the spinal discs, the cushions between the vertebrae, that sometimes cause back or neck pain. Discs lose water and height, and small tears form. Despite the name, it is not really a disease: disc degeneration shows up on MRI in most people over 40, many of whom have no pain. When it is painful, exercise, physical therapy and pain management help most people, and surgery is needed only for a small minority.
Also called: DDD, disc degeneration, intervertebral disc degeneration, spondylosis, degenerative disk disease
At a glance
- What it is
- Loss of water, height and resilience in spinal discs with age, sometimes painful.
- Where
- Most often the lower back (L4 to S1) and neck (C5 to C7).
- Symptoms
- Back or neck pain, worse with sitting, bending or lifting. Nerve pain if a disc presses on a nerve.
- Diagnosis
- History and examination. MRI only if red flags or nerve symptoms.
- Treatment
- Activity, exercise, physical therapy, pain relief. Surgery rarely.
- Outlook
- Pain usually comes in flares that settle, and often improves with age.
When to get help
Call 911 or go to the ER
- New numbness in the groin, buttocks or inner thighs (saddle area), loss of bladder or bowel control, or weakness in both legs, which can be cauda equina syndrome
- Back pain with fever, after recent infection, injection drug use or spinal procedures
See a doctor within a day or two
- Progressive weakness in an arm or leg, foot drop, or worsening numbness
- Back pain after significant trauma, or in someone with osteoporosis or cancer history
- Unexplained weight loss or night pain that does not ease with rest
Book a routine appointment
- Back or neck pain lasting more than 6 weeks despite self-care
- Pain spreading down an arm or leg with tingling
- Recurrent flares that limit work or sleep
Usually safe to manage at home
- A flare of back or neck pain without nerve symptoms or red flags, managed with movement, heat and pain relief
What happens in degenerative disc disease
Each disc has a tough outer ring (annulus fibrosus) and a gel-like center (nucleus pulposus). From early adulthood, discs gradually:
- lose water content and become flatter and stiffer
- develop small cracks in the outer ring
- bulge outward
As discs narrow, the load shifts to the facet joints at the back of the spine, which can develop arthritis. Bone spurs may form and narrow the spaces for nerves. These changes together are often called spondylosis.
Pain can come from the disc itself (nerve endings grow into damaged discs), from inflammation, from facet joints, or from nerves being pinched.
Symptoms
- Back pain or neck pain, often a dull ache with episodes of sharper pain
- worse with sitting, bending, lifting or twisting, and better with walking or lying down
- stiffness, especially in the morning
- flares lasting days to weeks, with quieter periods in between
Nerve symptoms
When a disc bulges or herniates, or the canal narrows, nerves can be pressed:
- Lower back: sciatica with pain, numbness or tingling down the leg
- Neck: pain, numbness or weakness down the arm (cervical radiculopathy)
- Spinal stenosis: leg pain and heaviness when walking, relieved by sitting or leaning forward
Causes and risk factors
- Age, the main factor
- Genetics, which explains much of why some people degenerate faster
- Smoking, which reduces blood supply to discs
- Obesity
- Heavy physical work, repetitive lifting and vibration
- Previous back injury
Disc degeneration on MRI: what it means
MRI findings are very common in people without pain. Large studies show disc degeneration in about a third of pain-free 20-year-olds and in most pain-free people over 60. A scan report that mentions "degenerative changes," "disc bulge" or "desiccation" does not, by itself, explain your pain or predict how you will do. This is why guidelines advise against routine MRI for back pain without red flags or nerve symptoms that may need surgery.
Diagnosis
A doctor takes a history and examines your back, posture, movement, reflexes, strength and sensation. Imaging is used when:
- there are red flags such as suspected infection, fracture, cancer or cauda equina syndrome
- nerve symptoms are severe or persist beyond about 6 weeks and treatment such as injection or surgery is being considered
MRI is the best test for discs and nerves. X-rays show disc space narrowing, bone spurs and alignment, such as spondylolisthesis.
Treatment
Stay active
Bed rest delays recovery. Keep moving within comfort, and return to normal activities gradually.
Exercise and physical therapy
- core strengthening and general conditioning
- walking, swimming and cycling
- stretching and mobility work
- yoga, Pilates and tai chi have evidence for chronic low back pain
- cognitive functional therapy addresses movement habits and fear of pain
Pain relief
- heat, massage and spinal manipulation can help in the short term
- NSAIDs such as ibuprofen or naproxen. Follow the label dose and check with a doctor if you have kidney, heart or stomach problems
- acetaminophen (paracetamol) has limited benefit for back pain alone
- short-term muscle relaxants for some flares
- nerve pain medicines such as duloxetine for chronic pain
- opioids are generally avoided for chronic back pain
Psychological approaches
Cognitive behavioral therapy and pain education reduce disability in chronic back pain, by addressing sleep, stress and fear of movement.
Injections
Epidural steroid injections can give short-term relief of nerve pain from a disc herniation. Facet joint injections and radiofrequency ablation help some people with facet-related pain.
Surgery
Surgery is considered for persistent nerve compression with weakness or severe pain, spinal stenosis that limits walking, instability, or cauda equina syndrome. Options include discectomy, decompression, spinal fusion and artificial disc replacement. Surgery for back pain from degeneration alone, without nerve compression, has modest results and is a last resort.
Outlook
Most flares improve within 6 weeks. Many people find that disc-related pain decreases with age as the spine stiffens and stabilizes. Staying active, maintaining a healthy weight and not smoking help keep symptoms under control.
Frequently asked questions
What are the symptoms of degenerative disc disease?
The main symptoms are back or neck pain and stiffness, worse with sitting, bending or lifting, often in flares. If a degenerated disc presses on a nerve, you may have pain, numbness, tingling or weakness down an arm or leg.
Is degenerative disc disease serious?
Usually not. It is a common, age-related process that many people have without pain. It can cause troublesome pain and nerve symptoms, but rarely leads to serious problems. Warning signs like loss of bladder control or leg weakness need urgent care.
Can degenerative disc disease be reversed?
The structural changes do not reverse, but pain usually improves. Exercise, physical therapy, weight management and stopping smoking reduce symptoms and improve function, even when MRI changes remain the same.
What should I avoid with degenerative disc disease?
Avoid prolonged sitting without breaks, heavy repetitive lifting with poor technique, smoking and long periods of bed rest. You do not need to avoid exercise. Staying active and building strength is one of the best treatments.
Does degenerative disc disease mean I need surgery?
Most people never need surgery. It is considered only for persistent nerve compression causing weakness or severe leg or arm pain, spinal stenosis limiting walking, or emergencies such as cauda equina syndrome, after good non-surgical treatment has been tried.
Sources
This guide was written from current patient and clinical guidance, including:
- American Academy of Orthopaedic Surgeons (OrthoInfo): Low Back Pain
- American College of Physicians: Noninvasive Treatments for Acute, Subacute and Chronic Low Back Pain (2017)
- North American Spine Society: Degenerative Disc Disease patient education
- NICE Guideline NG59: Low back pain and sciatica in over 16s
- MedlinePlus: Degenerative disc disease and back pain