Drug Allergy

Drug allergy is an immune-mediated reaction to a medication, distinct from common side effects. Reactions range from mild rashes to life-threatening anaphylaxis.

Table of Contents

Quick Facts

  • ICD-10: T88.7

Anaphylaxis Is an Emergency

Call 911 for hives, swelling of lips/tongue/throat, difficulty breathing, wheezing, dizziness, or fainting after taking a medication. Use epinephrine if available.

Common Culprits

  • Antibiotics (especially penicillin family)
  • NSAIDs and aspirin
  • Anti-seizure medications
  • Chemotherapy drugs
  • Sulfa drugs
  • IV contrast agents

Management

  • Stop the offending medication
  • Antihistamines and steroids for moderate reactions
  • Epinephrine for anaphylaxis
  • Document the allergy clearly on records
  • Wear medical-alert identification
  • Allergy testing or desensitization in selected cases

Related Conditions

Anaphylaxis

Severe form

 Angioedema

Related reaction

 Stevens-Johnson Syndrome

Severe drug reaction
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. If you are experiencing a medical emergency, call your local emergency number immediately.

References

  • American Academy of Allergy, Asthma & Immunology. Drug Allergies.