Coagulation Disorder
Coagulation disorders affect the body's ability to control bleeding and clotting. Some predispose to excessive bleeding, others to abnormal clotting. Many are treatable with specific factor replacement or medications.
Table of Contents
Quick Facts
- ICD-10: D68
Common Types
Bleeding disorders
- Hemophilia A and B
- Von Willebrand disease (most common inherited bleeding disorder)
- Platelet disorders
- Vitamin K deficiency
- Liver disease affecting clotting factors
Clotting disorders
- Factor V Leiden
- Prothrombin gene mutation
- Antiphospholipid syndrome
- Protein C or S deficiency
- Antithrombin deficiency
Signs
Bleeding disorders
- Easy or frequent bruising
- Prolonged bleeding from cuts, dental work, or surgery
- Heavy menstrual periods
- Joint bleeding (in hemophilia)
- Frequent nosebleeds
Clotting disorders
- Unprovoked blood clots (DVT, pulmonary embolism)
- Recurrent pregnancy loss
- Family history of clotting
Treatment
- Specific factor replacement for hemophilia
- Desmopressin for mild von Willebrand disease
- Anticoagulation for clotting disorders with clots
- Avoid certain medications (aspirin, NSAIDs) in bleeding disorders
- Genetic counseling for inherited forms
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. If you are experiencing a medical emergency, call your local emergency number immediately.
References
- American Society of Hematology. Bleeding and Clotting Disorders Resources.