SymptomWhole body & general
Loss of Libido: Causes and Treatment
Loss of libido is a noticeable drop in sexual desire compared with what is normal for you. It is common in both women and men and usually has more than one cause: stress, tiredness, depression, relationship problems, medicines such as antidepressants, and hormonal changes from menopause, pregnancy or low testosterone. It only needs treatment if it bothers you or your partner. Identifying the cause, often with a few blood tests and a medicine review, is the first step.
Also called: Low sex drive, decreased libido, reduced sexual desire, hypoactive sexual desire, loss of sexual interest
At a glance
- What it is
- Reduced interest in sex compared with your usual level.
- How common
- Very common; affects many women and men at some point.
- Main causes
- Stress, fatigue, depression and anxiety, relationship issues, medicines, hormonal changes, alcohol.
- Medical causes
- Low testosterone, high prolactin, thyroid disease, menopause, chronic illness.
- Tests
- Blood tests for testosterone, prolactin, thyroid, blood sugar; review of medicines.
- Treatment
- Treat the cause, adjust medicines, sex or couples therapy, and hormone therapy when indicated.
When to get help
See a doctor within a day or two
- Loss of libido with severe low mood, hopelessness or thoughts of self-harm: call or text 988 (US)
- Loss of libido with new severe headaches, vision changes or milky nipple discharge (possible pituitary tumor)
Book a routine appointment
- Loss of libido lasting more than a few months that causes you distress
- Loss of sex drive with erectile problems, loss of morning erections, reduced body hair or breast enlargement in men
- Low libido with irregular or absent periods, hot flashes or vaginal dryness
- Loss of libido that started after a new medicine
- Low libido with fatigue, weight change, feeling cold or excessive thirst
Usually safe to manage at home
- A temporary dip in desire during a stressful period, illness or after a new baby that is gradually improving
What counts as loss of libido?
Libido varies widely between people and changes across life. There is no "normal" amount of desire. Loss of libido matters when:
- it is a clear change from your usual level
- it lasts several months
- it causes you distress or strain in your relationship
When low desire is persistent and distressing, doctors may diagnose hypoactive sexual desire disorder. For a broader overview of low desire, see low libido.
Common causes of loss of libido
Psychological and lifestyle
- Stress and exhaustion: work, caregiving, money worries and lack of sleep are among the most common causes.
- Depression and anxiety: reduced pleasure and interest are core symptoms of depression.
- Relationship problems: conflict, poor communication, resentment, infidelity or loss of intimacy.
- Body image and self-esteem issues.
- Past sexual trauma.
- Alcohol and recreational drugs: heavy drinking, cannabis and opioids reduce desire over time.
Medicines
| Medicine group | Examples |
|---|---|
| Antidepressants | SSRIs (such as sertraline, fluoxetine) and SNRIs, very commonly |
| Hormonal contraceptives | Some combined pills in some women |
| Blood pressure medicines | Beta blockers, thiazide diuretics |
| Anti-androgens and prostate medicines | Finasteride, dutasteride, prostate cancer hormone therapy |
| Opioids | Long-term use lowers testosterone |
| Antipsychotics and anti-seizure medicines | Some raise prolactin or alter hormones |
| Antihistamines and sleeping pills | Sedation |
Do not stop a prescribed medicine on your own. Ask your doctor about alternatives, dose changes or adding a treatment.
Hormonal causes
- Menopause and perimenopause: falling estrogen and testosterone, plus vaginal dryness making sex uncomfortable.
- Pregnancy, after childbirth and breastfeeding: high prolactin and tiredness reduce desire for months.
- Low testosterone in men: low desire, fewer morning erections, fatigue, reduced muscle mass, low mood.
- High prolactin: from a pituitary tumor (prolactinoma) or medicines, sometimes with milky nipple discharge, irregular periods or erectile problems.
- Hypothyroidism: tiredness, weight gain, low mood and low libido.
Physical health conditions
- Diabetes, heart disease, kidney or liver disease
- Chronic pain and arthritis
- Cancer and its treatments
- Obesity and sleep apnea
- Painful sex from vaginal dryness, endometriosis, vaginismus or infections, which naturally reduces desire
- Erectile dysfunction, which can lead to avoiding sex and reduced desire
Loss of libido in women
Women's desire is often more responsive, arising during intimacy rather than spontaneously. Common contributors are tiredness, caregiving, relationship factors, pregnancy and breastfeeding, menopause, painful sex and antidepressants. Hormonal contraceptives affect libido in some women and not others.
Loss of libido in men
In men, loss of libido is more likely than erectile dysfunction alone to point to a hormonal problem such as low testosterone or high prolactin. Depression, stress, alcohol, opioids and medicines such as finasteride are other common causes. Testosterone naturally declines slowly with age, but a large drop is not a normal part of aging.
Sudden loss of libido
A sudden drop often follows a clear trigger: a new medicine (especially an antidepressant), a major stressor, a relationship crisis, childbirth, surgery or illness. Hormone causes usually develop gradually. If there is no obvious trigger, see your doctor.
How doctors find the cause
Your doctor will ask about your sexual history, relationships, mood, stress, alcohol and drug use, medicines, periods or menopause symptoms, and erections. They will examine you and may order blood tests:
- men: early-morning total testosterone, measured twice, with LH and FSH if low
- both: prolactin, thyroid function, blood sugar or HbA1c, blood count and sometimes kidney and liver tests
- women: hormone tests are less useful for diagnosis but may be checked for irregular periods or suspected early menopause
Treatment for loss of libido
Address the cause
- Medicine changes: switching antidepressants (for example to bupropion or mirtazapine) or adjusting doses can help.
- Treat depression, anxiety, thyroid disease or diabetes.
- Hormonal causes: testosterone therapy for confirmed testosterone deficiency in men; treatment of high prolactin with medicine.
Talk therapies
- Sex therapy and couples therapy are effective for many people, focusing on communication, reducing pressure and building intimacy.
- Cognitive behavioral therapy and mindfulness-based approaches help with desire problems in women.
For women around menopause
- Vaginal estrogen or moisturizers and lubricants ease dryness and pain during sex.
- Hormone therapy helps menopausal symptoms that affect desire.
- Testosterone may be offered by specialists to postmenopausal women with low desire after other causes are addressed. It is used off-label in some countries.
- Prescription medicines such as flibanserin and bremelanotide are approved in the US for low desire in premenopausal women, with modest effects and specific side effects.
Lifestyle
- Prioritize sleep and reduce stress.
- Exercise regularly, which improves energy, mood and body image.
- Cut down on alcohol and stop smoking.
- Make time for intimacy without pressure for intercourse.
Frequently asked questions
What causes a sudden loss of libido?
A sudden loss of libido usually follows a trigger such as starting an antidepressant or other medicine, a major stress, relationship difficulties, childbirth, illness or heavy alcohol use. Hormonal causes tend to develop more gradually. If there is no clear reason, ask your doctor for an assessment.
Can antidepressants cause loss of libido?
Yes. SSRIs and SNRIs commonly reduce desire, delay orgasm and cause erectile difficulties. Do not stop them suddenly. A doctor may adjust the dose, switch to an antidepressant with fewer sexual side effects such as bupropion, or add a treatment.
Is loss of libido a sign of low testosterone?
It can be, especially in men with fewer morning erections, fatigue, low mood and reduced muscle mass. A blood test taken in the early morning, repeated on a second day, confirms low testosterone. Many other causes, especially stress and depression, are more common.
How can I get my libido back?
Start by identifying the cause: review medicines, treat depression or anxiety, improve sleep, reduce alcohol, exercise and address relationship issues. Sex or couples therapy helps many people. If tests show a hormone problem, specific treatment can restore desire.
Is it normal for libido to drop with age?
Libido often changes with age, but a large drop is not inevitable. Menopause, falling testosterone, chronic illness, medicines and relationship changes all play a role, and many are treatable. Sexual desire can remain healthy well into later life.
Sources
This guide was written from current patient and clinical guidance, including:
- American College of Obstetricians and Gynecologists (ACOG): Female sexual dysfunction (Practice Bulletin)
- American Urological Association: Testosterone deficiency guideline
- NHS: Loss of libido (reduced sex drive)
- The Menopause Society: Sexual health and menopause
- MedlinePlus: Sexual problems in men; Sexual problems in women