Symptoms
- Fatigue, weakness, anemia
- Enlarged spleen — left upper abdominal fullness or pain
- Easy bruising or bleeding
- Night sweats, fever, weight loss
- Bone pain
- Itching
Treatment
- JAK inhibitors (ruxolitinib, fedratinib, momelotinib, pacritinib)
- Transfusions and erythropoiesis-stimulating agents for anemia
- Hydroxyurea for elevated counts
- Allogeneic stem cell transplant — potentially curative for selected patients
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. If you are experiencing a medical emergency, call your local emergency number immediately.
References
- MPN Research Foundation. Patient Resources.