G6PD Deficiency

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked inherited enzyme deficiency that makes red blood cells susceptible to hemolysis when exposed to certain medications, foods, or infections.

Table of Contents

Common Triggers

  • Fava beans (favism)
  • Antimalarials (primaquine)
  • Sulfa drugs
  • Nitrofurantoin
  • Methylene blue
  • Infections

Management

  • Avoid known triggers
  • Supportive care during hemolytic episodes
  • Genetic counseling
  • Newborn screening in some areas
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. If you are experiencing a medical emergency, call your local emergency number immediately.

References

  • ASH. G6PD Deficiency Resources.