Charcot-Marie-Tooth Disease

Charcot-Marie-Tooth (CMT) disease is a group of inherited disorders affecting the peripheral nerves, causing progressive weakness and sensory loss, primarily in the feet and lower legs.

Table of Contents

Symptoms

  • Weakness in the feet, then hands
  • High foot arches or flat feet
  • Hammertoes
  • Difficulty walking, frequent tripping
  • Numbness in feet and lower legs
  • Muscle wasting

Management

  • No cure; supportive care
  • Physical and occupational therapy
  • Orthotics, ankle braces
  • Foot surgery for severe deformities
  • Pain management
  • Avoid neurotoxic medications (e.g., vincristine)
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. If you are experiencing a medical emergency, call your local emergency number immediately.

References

  • CMTA. Patient Resources.