Malaise

Malaise is a vague feeling of being unwell — tired, off, not yourself — without a single specific symptom. It can accompany acute illness or signal something more serious when persistent.

Table of Contents

Quick Facts

  • ICD-10: R53.81

Common Causes

  • Viral or bacterial infections (often the first symptom)
  • Chronic medical conditions
  • Depression or anxiety
  • Sleep disorders
  • Medication side effects
  • Thyroid or adrenal disorders
  • Anemia
  • Chronic infections (HIV, TB, hepatitis)
  • Cancer

When to See a Doctor

  • Persistent malaise lasting weeks
  • Associated weight loss, fever, or night sweats
  • New severe symptoms developing
  • Significant impact on daily life

Related Symptoms

Fatigue

Related symptom

 Fever

Often coexists
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. If you are experiencing a medical emergency, call your local emergency number immediately.

References

  • American Academy of Family Physicians. Evaluation of Malaise.