Post-Streptococcal Glomerulonephritis
Post-streptococcal glomerulonephritis (PSGN) is inflammation of the kidney's filtering units that occurs 1–3 weeks after certain streptococcal infections. It mostly affects children and usually resolves on its own.
Quick Facts
- ICD-10: N00, N05
- Onset: 1–3 weeks after strep infection
- Outlook: Usually full recovery in children
Symptoms
- Tea or cola-colored urine
- Reduced urine output
- Swelling, especially around the eyes, legs, or abdomen
- High blood pressure
- Fatigue
Diagnosis
- Urinalysis (blood, protein, red cell casts)
- Blood tests (kidney function, complement levels)
- Streptococcal antibody titers (ASO, anti-DNase B)
- Kidney biopsy in unusual cases
Treatment
- Supportive care — usually self-limited
- Salt and fluid restriction during the acute phase
- Diuretics for edema
- Blood pressure control
- Antibiotics if active strep infection
- Dialysis rarely needed
Outlook
Most children recover fully within weeks. Adults may have a more variable course, and some develop persistent proteinuria or chronic kidney issues.
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. If you are experiencing a medical emergency, call your local emergency number immediately.
References
- American Society of Pediatric Nephrology. PSGN Patient Information.