Dyslipidemia

Dyslipidemia means abnormal levels of fats (lipids) in the blood — most commonly elevated LDL ('bad') cholesterol or triglycerides, and sometimes low HDL ('good') cholesterol. It is a major modifiable risk factor for heart disease and stroke.

Table of Contents

Quick Facts

  • ICD-10: E78
  • Major risk factor for: Heart disease, stroke
  • Treatment: Lifestyle + statins

Diagnosis

Lipid panel measures:

  • Total cholesterol
  • LDL cholesterol
  • HDL cholesterol
  • Triglycerides
  • Non-HDL cholesterol

Adult lipid screening is generally recommended starting in the 20s and repeated at intervals based on results and overall cardiovascular risk.

Causes

  • Genetics (familial hypercholesterolemia)
  • Diet high in saturated and trans fats
  • Excess weight and inactivity
  • Diabetes
  • Hypothyroidism
  • Kidney or liver disease
  • Some medications

Treatment

Lifestyle

  • Heart-healthy diet (Mediterranean or DASH patterns)
  • Regular physical activity
  • Healthy weight
  • Don't smoke; limit alcohol

Medications

  • Statins (mainstay for LDL lowering)
  • Ezetimibe
  • PCSK9 inhibitors
  • Bempedoic acid
  • Fibrates or omega-3 (especially for high triglycerides)
  • Niacin (less commonly used now)
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. If you are experiencing a medical emergency, call your local emergency number immediately.

References

  • ACC/AHA Guideline on the Management of Blood Cholesterol.