Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disorder in which the immune system damages the protective covering (myelin) of peripheral nerves, causing progressive weakness and sensory loss.

Table of Contents

Quick Facts

  • ICD-10: G61.81
  • Treatable: Yes

Symptoms

  • Progressive symmetric weakness in arms and legs
  • Numbness or tingling
  • Reduced reflexes
  • Fatigue
  • Difficulty walking or with fine motor tasks

Develops over weeks to months, distinguishing it from Guillain-Barré syndrome (days to weeks).

Treatment

  • Corticosteroids
  • IV immunoglobulin (IVIG) or subcutaneous Ig
  • Plasma exchange
  • Immunosuppressants for refractory cases
  • Physical and occupational therapy

Related Conditions

Guillain-Barre Syndrome

Acute counterpart

 Multifocal Motor Neuropathy

Related immune neuropathy
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. If you are experiencing a medical emergency, call your local emergency number immediately.

References

  • GBS/CIDP Foundation International. CIDP Resources.