Cavernous Sinus Thrombosis

Cavernous sinus thrombosis is a blood clot in a large vein at the base of the skull, usually from facial or sinus infection. It is rare but life-threatening, requiring urgent IV antibiotics and sometimes anticoagulation.

Table of Contents

Quick Facts

  • ICD-10: G08
  • Severity: Life-threatening emergency

Emergency Warning

Seek emergency care for:
  • Severe headache with fever
  • Swelling, redness, and pain around one eye
  • Bulging eye, drooping eyelid, double vision
  • Following a facial infection (especially around nose, mouth, sinus)

Causes

  • Sinusitis, especially sphenoid sinus
  • Facial cellulitis or abscess (do not squeeze pimples in the danger triangle)
  • Dental infections
  • Ear or mastoid infections

Treatment

  • Hospitalization with high-dose IV antibiotics
  • Anticoagulation in selected cases
  • Treatment of source of infection (drainage)
  • Supportive care
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. If you are experiencing a medical emergency, call your local emergency number immediately.

References

  • Infectious Diseases Society of America. CNS Infection Resources.