Acute Myeloid Leukemia (AML)
Acute myeloid leukemia (AML) is a fast-growing cancer of the bone marrow and blood. It is the most common acute leukemia in adults. Modern therapy combines chemotherapy, targeted agents, and often stem cell transplant.
Quick Facts
- ICD-10: C92.0
- Severity: Aggressive — needs urgent care
Symptoms
- Fatigue, pale skin (anemia)
- Frequent infections and fever (low neutrophils)
- Easy bruising and bleeding (low platelets)
- Bone or joint pain
- Swollen lymph nodes (less common in AML than ALL)
- Shortness of breath
Diagnosis
- Complete blood count with blasts on smear
- Bone marrow biopsy
- Cytogenetic and molecular testing (drives treatment)
Treatment
- Induction chemotherapy (often "7+3" regimen)
- Targeted therapies (FLT3, IDH inhibitors, venetoclax combinations)
- Consolidation therapy
- Allogeneic stem cell transplant for higher-risk disease
- Clinical trials
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. If you are experiencing a medical emergency, call your local emergency number immediately.
References
- NCCN. AML Guidelines.